Cosmetic Grade Hyaluronic Acid, Sodium Hyaluronate Powder
Sodium hyaluronate widely exists in human and animal tissues and cells. It plays an important role in preventing skin aging, improving the touch and appearance of the skin. Some low molecular weight hyaluronic acid can also penetrate into the dermis of the skin, improving and regulating the metabolism of the skin, making the skin moist, smooth, delicate, tender and elastic, thus playing the role of wrinkle prevention and beauty care, At the same time of moisturizing, it also plays a good role in promoting transdermal absorption.
Cosmetic Grade Hyaluronic Acid, Sodium Hyaluronate Powder
INCI Name: Sodium Hyaluronate
Chemical Name: Hyaluronic Acid, Sodium salt
Synonyms: Mucoitin, Sepracoat, Hyaluronic acid, Hydluronic acid, Hyalobarrier gel, aluronic acid, HA, Haluronic acid,Chlamyhyaluronic acid, Hyaluronic acid powder, Hyaluronic acid sodium
EINECS/ELNICS: 232-678-0
CAS No.: 9004-61-9(hyaluronic acid), 9067-32-7(Sodium hyaluronate)
Molecular Formula:
hyaluronic acid-(C14H21NO11)n,
Sodium hyaluronate -(C14H20NO11Na)n
Sodium hyaluronate is a linear chain muco-polysaccharide composed of disaccharide units formed from D-glucuronic acid & N acetylglucosamine held together by β 1,3 linkages.
Production Method: Fermentation
Bacteria Source: Streptococcus Zooepidemicus
Specification/Molecular Weight (Dalton):
1. Ultra-low molecular weight sodium hyaluronate＜10,000Da
2. LMW/low molecular weight: 200,000 – 600,000 Dalton
3. Medium molecular weight: 800,000-1,600,000 Dalton
4. HMW/high molecular weight: > 1,800,000 Dalton
Purity: 93%(Min)
Intrinsic viscosity: 0.19-36.3dL/g
Appearance: White crystalline power
Particle size: 100% pass 80 mesh
Package: 100g/sterile bottle; 1kg/ aluminum foil bag; 25KG/ fiber drum
Storage: Stored in cool and dry place, at the temperature of 2-10℃
Shelf life: 2 years without opening the package
Application:
Skin care products: cream, emulsion, essence, emulsion, gel, mask , etc.
Beauty products: lipstick, eye shadow, foundation, etc.
Cleaning products: facial cleanser, bath lotion, etc.
Hair products: shampoo, conditioner, styling gel, etc.
Introduction
Hyaluronic acid/sodium hyaluronate is a natural biological molecule widely existing in skin and other tissues. It has excellent moisturizing effect and is called an ideal natural moisturizing factor in the world. It is the best moisturizing substance found in nature for cosmetics at present.
Hyaluronic acid acts on skin surface
Macromolecular hyaluronic acid/sodium hyaluronate (with molecular weight ranging from 1,800,000 to 2,200,000 Dalton) can form a permeable film on the skin surface, which makes the skin smooth and moist, and can prevent the invasion of foreign bacteria, dust and ultraviolet rays, and protect the skin from invasion.
Medium molecular hyaluronic acid/sodium hyaluronate (molecular weight range 1,000,000-1,800,000 Dalton) can tighten the skin and keep it moist for a long time.
Small molecule hyaluronic acid/sodium hyaluronate (molecular weight range 400,000-1,000,000 Dalton) can penetrate into dermis. It has the functions of slightly expanding capillaries, increasing blood circulation, improving intermediate metabolism and promoting skin nutrient absorption. It has strong wrinkle-relieving function, increasing skin elasticity and delaying skin aging. Measuring a good skin care product is based on three different molecular weight of hyaluronic acid ingredients as the standard, only containing a single molecular weight of hyaluronic acid ingredients of skin care products have limited effect, can not play the best skin care effect of hyaluronic acid.
Hyaluronic acid/sodium hyaluronate can also promote the proliferation and differentiation of epidermal cells, scavenge oxygen free radicals, and prevent and repair skin damage. The aqueous solution of hyaluronic acid has high viscosity and can thicken the water phase. The paste emulsified with oil phase is uniform and delicate, and has stable emulsification effect. Hyaluronic acid is the best natural moisturizing ingredient of high-grade cosmetics. It has good compatibility and can be added to any cosmetic products. It is widely used in cosmetics, such as cream, lotion, make-up water, essence, facial cleanser, bath shampoo, shampoo and extender, mousse, lipstick and so on. And the suggested addition amount is 0.05 – 0.5% for cosmetic application.
Certificate of Analysis
| Item | Standard | Result |
| Appearance | White powder | White powder |
| Glucuronic Acid | ≥ 45% | 47.69% |
| Sodium Hyaluronate | ≥ 93% | 98.56% |
| Appearance of Solution | A600nm≤ 0.01 | Complied |
| Nucleic Acid | A260nm≤ 0.5 | Complied |
| pH | 6.0-7.5 | 6.50 |
| Molecular Weight | 1.0-1.5Million Daltons | 1.2Million Daltons |
| Protein | ≤0.05% | 0.03% |
| Loss on drying | ≤10% | 6.0% |
| Residue on Ignition | ≤20.00 % | 10.85% |
| Chlorides | ≤ 0.5% | 0.3% |
| Iron | ≤ 80ppm | ＜80ppm |
| Heavy metal | ≤10ppm | ＜10ppm |
| Arsenic | ≤2ppm | ＜2ppm |
| Bacteria Count | ≤100CFU/G | ＜100CFU/G |
| Molds & Yeast | ≤10CFU/g | ＜10CFU/G |
| Staphylococcus aureus | Negative | Negative |
| Pseudomonas aeruginosa | Negative | Negative |
| Hemolysis | Negative | Negative |
| Viable Hemolytical Streptococci | Negative | Negative |
| Conclusion | Complied with EP4.0 | |
| Shelf Life | Two Years | |
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